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<div style="text-align:left; border-width:2px; border-style:solid; border-color:white; border-bottom: 0; padding-left: 5px;">WARNING: CIGARETTE SMOKING AND SERIOUS CARDIOVASCULAR EVENTS</div>

IMPORTANT SAFETY INFORMATION

<div style="text-align:left;"> <div style="text-align:left; border-width:2px; border-style:solid; border-color:black; padding-left: 5px;"> WARNING: CIGARETTE SMOKING AND SERIOUS CARDIOVASCULAR EVENTS See full prescribing information for complete boxed warning. <ul class="list-d"> <li class="fw-b padL25" >Females over 35 years old who smoke should not use ANNOVERA.</li> </ul> <ul class="list-d"> <li class="fw-b padL25" >Cigarette smoking increases the risk of serious cardiovascular events from combination hormonal contraceptive use.</li> </ul> </div> <ul class="list-d"> 	<li class="fw-b padL25" >Do not use ANNOVERA (segesterone acetate and ethinyl estradiol vaginal system) if you smoke cigarettes and are over 35 years old. Smoking increases your risk of serious heart and blood vessel (cardiovascular) side effects from hormonal birth control methods, including death from heart attack, blood clots, or stroke. This risk increases with age and the number of cigarettes you smoke.</li> </ul> <ul class="list-d"> 	<li class="fw-b padL25">ANNOVERA does not protect against HIV infection (AIDS) and other sexually transmitted infections.</li> </ul> <ul class="list-d"> 	<li class="padL25">The use of a combination hormonal contraceptive (CHC), like ANNOVERA, is associated with increased risks of several serious side effects, including blood clots, stroke, or heart attack. Do not use ANNOVERA if you have a history of these conditions, have reduced blood flow to your brain (cerebrovascular disease) or reduced blood flow or blockage in any of the arteries that supply blood to your heart (cardiovascular disease), or any condition that makes your blood more likely to clot. The risk of blood clots is highest when you first start using CHCs and when you restart the same or different CHC after not using it for 4 weeks or more.</li> </ul> <ul class="list-d"> 	<li class="padL25">ANNOVERA is also not for women with high blood pressure that medicine can’t control or high blood pressure with blood vessel damage; diabetes and over 35 years old, diabetes with high blood pressure or kidney, eye, nerve, or blood vessel damage, diabetes for longer than 20 years; certain kinds of severe migraine headaches; liver disease or liver tumors; breast cancer or any cancer that is sensitive to the female hormones estrogen or progesterone; unexplained vaginal bleeding; are allergic to segesterone acetate, ethinyl estradiol or any other ingredients in ANNOVERA; or take any Hepatitis C drug combination containing ombitasvir/paritaprevir/ritonavir, with or without dasabuvir, as this may increase levels of the liver enzyme “alanine aminotransferase” (ALT) in the blood.</li> </ul> <ul class="list-d"> 	<li class="padL25">ANNOVERA can cause serious side effects, including: blood clots; toxic shock syndrome (TSS); liver problems, including liver tumors; high blood pressure; gallbladder problems; changes in the sugar and fat (cholesterol and triglycerides) levels in your blood; headache; irregular or unusual vaginal bleeding and spotting between your menstrual periods; depression; possible cancer in your cervix; swelling of your skin especially around your mouth, eyes, and in your throat (angioedema); dark patches of skin on your forehead, cheeks, upper lip, and chin (chloasma). Call your healthcare provider or get emergency medical care right away if any of these serious side effects occur.</li> </ul> <ul class="list-d"> 	<li class="padL25">The most common side effects reported in at least 5% of women who received ANNOVERA were: headache/migraine, nausea/vomiting, vaginal yeast infection (candidiasis), lower/upper abdominal pain, painful periods, vaginal discharge, urinary tract infection, breast pain/tenderness, irregular vaginal bleeding, diarrhea, and genital itching.</li> </ul> <h2 style=margin-bottom:12px; margin-top:8px;">USE</h2> ANNOVERA is a ring-shaped vaginal system with hormones used by females to prevent pregnancy. ANNOVERA has not been adequately studied in females with a body mass index &gt;29 kg/m2. The risk information provided here is not complete. To learn more, review the ANNOVERA Patient Information and talk with your healthcare provider or pharmacist. The FDA-approved product labeling, including Patient Information, can be found <a target="_blank" class="css-1rn59kg" title="https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=37bb9ebd-2e99-4453-bbe6-9dd4a2897193&amp;type=display" href="https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=37bb9ebd-2e99-4453-bbe6-9dd4a2897193&type=display" data-testid="link-with-safety" data-renderer-mark="true">here</a>. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit <a target="_blank" href="http://www.fda.gov/medwatch">http://www.fda.gov/medwatch</a> or call 1-800-FDA-1088. </div>

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It lasts for 13 cycles, which is a whole year*, if you’re counting.
*Each cycle, leave it in for 21 days and then leave it out for 7 days. Repeat for 13 cycles.

IT'S ANNUAL

It’s soft and squishy, because where it goes is soft and squishy.

IT'S COMFORTABLE

You put it in (and leave it in for 21 days), and you pull it out (and leave out for 7 days). Imagine that.

IT'S CONTROLLABLE

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We believe that women shouldn't have to apologize for anything regarding their sexual health. It's time we stop apologizing and start demanding more from our birth control. Speak to an UpScript physician today to determine if ANNOVERA may be right for you.

Rx request reviewed by healthcare professional (HCP)

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Medication sent directly to your home or office

Unapologetically, ANNOVERA.

<div style="color: white">Please see Important Safety Information, including Boxed Warning, below.</div>

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<div style="text-align:left; border-width:2px; border-style:solid; border-color:white; border-bottom: 0; padding-left: 5px;"> WARNING: CIGARETTE SMOKING AND SERIOUS CARDIOVASCULAR EVENTS</div>

Annual, comfortable, controllable birth control. Finally. It's time we stop apologizing and start demanding more from our birth control. So, we made ANNOVERA &mdash; a soft and squishy birth control ring that lasts for a whole year*, no procedure required. *Each cycle, leave it in for 21 days and then leave it out for 7 days. Repeat for 13 cycles.

Meet ANNOVERA®

Speak to a healthcare provider on your schedule from your own home.

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See if ANNOVERA is right for you.

Get your prescription approved via a quick and affordable virtual appointment.

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Connect with a healthcare provider.

Home delivery of your ANNOVERA prescription.

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Flexible fulfillment options.

ANNOVERA is the first and only long-lasting, procedure-free birth control that lasts a whole year*. *Each cycle, leave it in for 21 days and then leave it out for 7 days. Repeat for 13 cycles.

What is ANNOVERA?

<div style="text-align:left;">
<div style="text-align:left; border-width:2px; border-style:solid; border-color:black; padding-left: 5px;">
WARNING: CIGARETTE SMOKING AND SERIOUS CARDIOVASCULAR EVENTS
 
See full prescribing information for complete boxed warning.
 
<ul class="list-d">
<li class="fw-b padL25" >Females over 35 years old who smoke should not use ANNOVERA.</li>
</ul>
<ul class="list-d">
<li class="fw-b padL25" >Cigarette smoking increases the risk of serious cardiovascular events from combination hormonal contraceptive use.</li>
</ul>

</div>
<ul class="list-d">
 	<li class="fw-b padL25" >Do not use ANNOVERA (segesterone acetate and ethinyl estradiol vaginal system) if you smoke cigarettes and are over 35 years old. Smoking increases your risk of serious heart and blood vessel (cardiovascular) side effects from hormonal birth control methods, including death from heart attack, blood clots, or stroke. This risk increases with age and the number of cigarettes you smoke.</li>
</ul>
<ul class="list-d">
 	<li class="fw-b padL25">ANNOVERA does not protect against HIV infection (AIDS) and other sexually transmitted infections.</li>
</ul>
<ul class="list-d">
 	<li class="padL25">The use of a combination hormonal contraceptive (CHC), like ANNOVERA, is associated with increased risks of several serious side effects, including blood clots, stroke, or heart attack. Do not use ANNOVERA if you have a history of these conditions, have reduced blood flow to your brain (cerebrovascular disease) or reduced blood flow or blockage in any of the arteries that supply blood to your heart (cardiovascular disease), or any condition that makes your blood more likely to clot. The risk of blood clots is highest when you first start using CHCs and when you restart the same or different CHC after not using it for 4 weeks or more.</li>
</ul>
<ul class="list-d">
 	<li class="padL25">ANNOVERA is also not for women with high blood pressure that medicine can’t control or high blood pressure with blood vessel damage; diabetes and over 35 years old, diabetes with high blood pressure or kidney, eye, nerve, or blood vessel damage, diabetes for longer than 20 years; certain kinds of severe migraine headaches; liver disease or liver tumors; breast cancer or any cancer that is sensitive to the female hormones estrogen or progesterone; unexplained vaginal bleeding; are allergic to segesterone acetate, ethinyl estradiol or any other ingredients in ANNOVERA; or take any Hepatitis C drug combination containing ombitasvir/paritaprevir/ritonavir, with or without dasabuvir, as this may increase levels of the liver enzyme “alanine aminotransferase” (ALT) in the blood.</li>
</ul>
<ul class="list-d">
 	<li class="padL25">ANNOVERA can cause serious side effects, including: blood clots; toxic shock syndrome (TSS); liver problems, including liver tumors; high blood pressure; gallbladder problems; changes in the sugar and fat (cholesterol and triglycerides) levels in your blood; headache; irregular or unusual vaginal bleeding and spotting between your menstrual periods; depression; possible cancer in your cervix; swelling of your skin especially around your mouth, eyes, and in your throat (angioedema); dark patches of skin on your forehead, cheeks, upper lip, and chin (chloasma). Call your healthcare provider or get emergency medical care right away if any of these serious side effects occur.</li>
</ul>
<ul class="list-d">
 	<li class="padL25">The most common side effects reported in at least 5% of women who received ANNOVERA were: headache/migraine, nausea/vomiting, vaginal yeast infection (candidiasis), lower/upper abdominal pain, painful periods, vaginal discharge, urinary tract infection, breast pain/tenderness, irregular vaginal bleeding, diarrhea, and genital itching.</li>
</ul>
<h2 style=margin-bottom:12px; margin-top:8px;">USE</h2>
ANNOVERA is a ring-shaped vaginal system with hormones used by females to prevent pregnancy.
ANNOVERA has not been adequately studied in females with a body mass index &gt;29 kg/m2.

The risk information provided here is not complete. To learn more, review the ANNOVERA Patient Information and talk with your healthcare provider or pharmacist. The FDA-approved product labeling, including Patient Information, can be found <a target="_blank" class="css-1rn59kg" title="https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=37bb9ebd-2e99-4453-bbe6-9dd4a2897193&amp;type=display" href="https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=37bb9ebd-2e99-4453-bbe6-9dd4a2897193&type=display" data-testid="link-with-safety" data-renderer-mark="true">here</a>.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit <a target="_blank" href="http://www.fda.gov/medwatch">http://www.fda.gov/medwatch</a> or call 1-800-FDA-1088.

</div>

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UpScript gives you fast access to trusted prescription medication. Select your treatment, speak with a private online doctor and get it delivered right to your doorstep.

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Upscript Health QA

Still curious? Here’s what other men are asking

Tadalafil is a phosphodiesterase 5 (PDE5) inhibitor indicated for the treatment of erectile dysfunction (ED). Read below for important safety information about Tadalafil. 

If take as needed, the starting dose is 10 mg as needed prior to sexual activity. Increase to 20 mg or decrease to 5 mg based upon efficacy/tolerability. Improves erectile function compared to placebo up to 36 hours post dose. Not to be taken more than once per day.
&nbsp;
If take TADALAFIL FOR ONCE DAILY USE, the recommended starting dose is 2.5 mg, taken at approximately the same time every day, without regard to timing of sexual activity. The dose may be increased to 5 mg, based on individual efficacy and tolerability.

<ul>
<li>Patients should not use TADALAFIL if sex is inadvisable due to cardiovascular status.</li>
<li>Use of TADALAFIL with alpha-blockers, antihypertensives or substantial amounts of alcohol (≥5 units) may lead to hypotension.</li>
<li>Caution is advised when TADALAFIL is used as a treatment for ED in men taking alpha-blockers.</li>
<li>Patients should seek emergency treatment if an erection lasts &gt;4 hours. Use TADALAFIL with caution in patients predisposed to priapism.</li>
<li>Patients should stop TADALAFIL and seek medical care if a sudden loss of vision occurs in one or both eyes, which could be a sign of non-arteritic anterior ischemic optic neuropathy (NAION). TADALAFIL should be used with caution, and only when the anticipated benefits outweigh the risks, in patients with a history of NAION. Patients with a “crowded” optic disc may also be at an increased risk of NAION.</li>
<li>Patients should stop TADALAFIL and seek prompt medical attention in the event of sudden decrease or loss of hearing.</li>
</ul>

<ul>
<li>Administration of TADALAFIL to patients using any form of organic nitrate is contraindicated. TADALAFIL was shown to potentiate the hypotensive effect of nitrates.</li>
<li>History of known serious hypersensitivity reaction to TADALAFIL or ADCIRCA®.</li>
<li>Administration with guanylate cyclase (GC) stimulators, such as riociguat.</li>
</ul>

Most common adverse reactions (≥2%) include headache, dyspepsia, back pain, myalgia, nasal congestion, flushing, and pain in limb.
&nbsp;
To report SUSPECTED ADVERSE REACTIONS, call or report via the FDA MedWatch Program at <a href="http://www.fda.gov/safety/medwatch-fda-safety-information-and-adverse-event-reporting-program" target="_blank" rel="noopener">www.fda.gov/medwatch </a> or 1-800-FDA-1088.

Important Safety Information

Erectile Dysfunction may be taboo, but we’re here to change that. Because guess what? You’re not alone—ED affects about 30 million men in the U.S. That’s where we come in — UpScript offers Tadalafil (generic Cialis), a simple and effective solution that makes ED optional.

You’re not alone.

Tadalafil is the active ingredient in Cialis that helps men with ED improve sexual function with harder and longer-lasting erections. Tadalafil helps you get and maintain your erections through a simple, daily dosage—regardless of how often you have sex. Fill out our quick online consultation to get started with treatment today.

Stay ready so you don’t have to get ready.

Tadalafil has been proven to help guys with varying degrees of ED. UpScript makes it easy to get Tadalafil shipped discreetly & directly to you. With a solution this easy, there’s no excuse not to get back in the game. Get started with our quick online questionnaire.

It's easy to get back in the game.

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You know it by another name: Cialis. Tadalafil can be taken as-needed or daily so you’re always ready for action. Taken on a regular basis, tadalafil can allow for more spontaneity so you're covered around the clock.

Tadalafil

Tadalafil can be taken as-needed or daily so you’re always ready for action. Talk to a doctor and get tadalafil delivered to your door.